Biosafety Cabinets represent safety procedures and technology in biomedical laboratories to prevent unintentional exposure to virulent viruses, pathogens, contaminants or their accidental release.
Similar to this, PCR (Polymerase Chain Reaction), is a typical laboratory technique for quickly amplifying billions of copies of a specific DNA segment for additional research and experiments. In the PCR method, experts choose a portion of the genome to be amplified and carry out numerous rounds of DNA synthesis using primers, which are short synthetic DNA fragments.
How do Biosafety Cabinets work?
PCR programmes and Biosafety Cabinets-both are essential for researching more about the rapid spread of monkeypox outbreaks after COVID-19.
Biosafety cabinets are devices for contamination control and protection. They work in Biological Safety Level 2 or Level 3 (BSL 2 or BSL 3) laboratories with biological agents to maintain a secure working environment for lab personnel and safeguard clinical specimens and suspected samples from microbes or visible organisms. Biosafety cabinets are crucial in clinical or biomedical labs as a benchmark of standard precautions, particularly during Monkeypox research procedures.
Biosafety cabinets work in a sequence of four levels. These are essential in lab settings where workers are exposed to lethal viruses, such as Monkeypox. Therefore, by releasing three different types of HEPA-filtered air—inward, downward, and exhaust—it safeguards people, products, suspected samples and the surrounding environment.
How does PCR work?
Often called molecular photocopying, PCR is a quick and economical method that enables researchers to analyze billions of isolated DNA samples. It is a meaningful application for diagnosing genetic disorders or mutations and detecting viruses or bacteria in clinical and laboratory settings.
In fact, PCR also plays an essential role in learning more about the highly virulent Monkeypox by providing a complete safe and sterile work chamber for personnel actively researching on finding a viable vaccine for the virus.
Are Biosafety Cabinets and PCR helpful in Monkeypox research?
MPXV, often known as the Monkeypox Virus, is a member of orthopox virus that is just as harmful and contagious as smallpox.
Recent reports of Monkeypox cases in humans across the globe are a classic example of how urgently the world needs a vaccine or antiviral treatment.
However, because it is contagious, a SEM laboratory undertaking research and testing for Monkeypox antivirals need a secure workplace with the maximum level of sterility and bio-containment from any accidental release.
Alpha Linear’s Class II Biosafety Cabinets are optimal for handling harmful biological samples during studies and clinical trials in microbiological laboratories. It creates a sterile workzone by streamlining the inflow and downflow air that passes through a series of HEPA filters. It creates an ISO Class 3 working environment and protects personnel and samples from hazardous pollutant exposure.